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Study Updates

May 25, 2017

It’s been a while since you’ve heard from us here at the Cambridge Centre for Neuropsychiatric Research (CCNR). We’ve been doing a lot of work to analyse the 550 dried blood spot samples you sent us! We’d like to emphasize again how grateful we are for your generous support of our study.

We measured the concentrations of 94 different proteins in your dried blood spots using mass spectrometry technology. We then conducted a statistical analysis of these proteins and your questionnaire responses, from which we have some interesting and very promising results. We hope these results will contribute to development of a diagnostic test for bipolar disorder and major depressive disorder. This has the potential to lead to earlier diagnosis and treatment of these disorders, improve our understanding of them, and produce better outcomes for patients.

We will be publishing a full account of these results in a scientific journal (these things take time, so please have patience with us!). As always, we will keep updating our website and Facebook/Twitter pages to keep you informed.

In the meantime, we will be launching a follow-up study to the Spot Depression study this year. This will consist of a carefully designed digital questionnaire to be completed over the course of several days (with plenty of interesting and helpful material included)! The digital questionnaire can be answered online on a desktop computer or mobile device and will consist of questions about your personality, lifestyle, psychiatric symptoms and history, and other factors important to mental wellbeing. We will be seeking individuals experiencing depressive symptoms for this study, and particularly those with a prior diagnosis of bipolar disorder or major depressive disorder. If you meet the criteria and are willing to help, your experience in the Spot Depression study would make you an incredibly valuable participant for us. We will publish an update with more information when we begin recruitment for this study. 

Thanks again for your valuable contributions!


September 14, 2016

We have received over 550 dried blood spot cards from participants in the Spot Depression study! We are now in the process of preparing samples for analysis by mass spectrometry. 


August 04, 2016

Thank you to everyone who has helped with our study! We have now closed recruitment. We will keep you all updated via our website and our Facebook and Twitter pages.


June 25, 2016

Thanks to everyone who has participated in our Spot Depression study! We have had an overwhelming number of sign-ups and are immensely grateful for your support of our research. We are now carefully going through your responses and will contact you via email to let you know whether or not you will receive a kit. If you have not yet received an email, we appreciate your patience.

We are still looking for controls who have not been diagnosed with any psychiatric disorder - please do fill out our online questionnaire at if you meet this criteria. We are hoping to close the study soon and will keep you all updated.